In the tradition of UNDERWORLD and DISTRICT 9, all of Manhattan is quarantined when the Lupine virus spreads like wildfire, turning innocent civilians into ravenous wolves. Nothing short of a nuclear blast can stop the monstrous virus.
A group of siblings go to their family cabin after over a decade for a hunting trip to reconnect, only to find themselves being hunted by a terrifying alien creature. Now they must team up and become the hunters before becoming the hunted.