Murdoch is in Bristol, England, with no memory of who he is and two gunmen chasing him through the streets. With the help of a local pub Landlady he starts to piece together an assassination plot. In Toronto Detective Hamish Sloack is assigned to help find the missing Murdoch.
CIA的反恐行动已经接近尾声,Joe(佐伊·索尔达娜 Zoe Saldana 饰)、Kaitlyn(妮可·基德曼 Nicole Kidman 饰)和Byron(迈克尔·凯利 Michael Kelly 饰)招募了一名新特工来潜入一个以前不为人知的威胁。随着来自各方的压力越来越大,Joe作为“母狮”计划的领导者,必须做出巨大的个人牺牲。